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Nota is a Linux open-source (GPL license) todo manager written in Python. Its GUI uses GTK through the PyGTK library.
Nota is designed to be very small and very easy to use, so don't expect a lot of bells and whistles. If you want a more powerful manager, take a look at Gtodo or Evolution.
The latest version is 0.02, get it on the download page. Nota is still in early stage of development, so don't expect too much of the current version.